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1

Recurrent meningococcal sepsis in a presumptive immunocompetent host shown to be complement C5 deficient—a case report

GRO GRIMNES, HANS BECKMAN, KNUT TORE LAPPEGÅRd, TOM EIRIK MOLLNES, VEGARD SKOGEN

Journal:

Year:

2011

Language:

english

File:

PDF, 122 KB

english, 2011

2

Primary complement C5 deficiencies – Molecular characterization and clinical review of two families

Schejbel, Lone, Fadnes, Dag, Permin, Henrik, Lappegård, Knut Tore, Garred, Peter, Mollnes, Tom Eirik

Journal:

Year:

2013

Language:

english

File:

PDF, 1.38 MB

english, 2013

3

Persisting thrombin activity in elderly patients with atrial fibrillation on oral anticoagulation is decreased by anti-inflammatory therapy with intensive cholesterol-lowering treatment

Janet van Kuilenburg, Knut Tore Lappegård, Joe Sexton, Izabela Plesiewicz, Paul Lap, Leon Bouwels, Tom Sprong, Tom Eirik Mollnes, Freek Verheugt, Waander L. van Heerde, Gheorghe A. Pop

Journal:

Journal of Clinical Lipidology

Year:

2011

Language:

english

File:

PDF, 387 KB

english, 2011

4

Fecal microbiota transplantation in irritable bowel syndrome does not affect plasma lipids or LDL and HDL subfractions

Kjellmo, Christian Abends, Johnsen, Peter Holger, Hovland, Anders, Lappegård, Knut Tore, Mathisen, Monica

Journal:

Atherosclerosis

Year:

2017

Language:

english

File:

PDF, 53 KB

english, 2017

5

Granulocyte and monocyte CD11b expression during plasma separation is dependent on complement factor 5 (C5) - an ex vivo study with blood from a C5-deficient individual

Hardersen, Randolf, Enebakk, Terje, Christiansen, Dorte, Bergseth, Grethe, Brekke, Ole-Lars, Mollnes, Tom Eirik, Lappegård, Knut Tore, Hovland, Anders

Journal:

Year:

2018

Language:

english

File:

PDF, 566 KB

english, 2018

6

The dependence of C5 on artificial surface-induced inflammatory reactions: Evidence from a C5-deficient individual

Grethe Bergseth, John D. Lambris, Knut Tore Lappegård, Tom Eirik Mollnes

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 88 KB

english, 2008

7

Lifestyle Changes Followed by Bariatric Surgery Lower Inflammatory Markers and the Cardiovascular Risk Factors C3 and C4

Nestvold, Torunn Kristin, Nielsen, Erik Waage, Ludviksen, Judith Krey, Fure, Hilde, Landsem, Anne, Lappegård, Knut Tore

Journal:

Metabolic Syndrome and Related Disorders

Year:

2015

Language:

english

File:

PDF, 233 KB

english, 2015

8

Side effects in LDL apheresis: types, frequency and clinical relevance

Lappegård, Knut Tore, Hovland, Anders

Journal:

Clinical Lipidology

Year:

2011

Language:

english

File:

PDF, 459 KB

english, 2011

9

Addition of marine omega-3 fatty acids to statins in familial hypercholesterolemia does not affect in vivo or in vitro endothelial function

Hande, Liv Nesse, Thunhaug, Hilde, Enebakk, Terje, Ludviksen, Judith, Pettersen, Kristin, Hovland, Anders, Lappegård, Knut Tore

Journal:

Journal of Clinical Lipidology

Year:

2019

Language:

english

File:

PDF, 642 KB

english, 2019

10

Comparison of cytokine changes in three different lipoprotein apheresis systems in an ex vivo whole blood model

Hardersen, Randolf, Enebakk, Terje, Christiansen, Dorte, Ludviksen, Judith K., Mollnes, Tom E., Lappegård, Knut Tore, Hovland, Anders

Journal:

Journal of Clinical Apheresis

Year:

2019

Language:

english

File:

PDF, 2.72 MB

english, 2019

11

Comparison of cytokine changes in three different lipoprotein apheresis systems in an ex vivo whole blood model

Hardersen, Randolf, Enebakk, Terje, Christiansen, Dorte, Ludviksen, Judith K., Mollnes, Tom E., Lappegård, Knut Tore, Hovland, Anders

Journal:

Journal of Clinical Apheresis

Year:

2019

File:

PDF, 2.72 MB

2019

12

Different inflammatory responses induced by three LDL-lowering apheresis columns

Anders Hovland, Randolf Hardersen, Joe Sexton, Tom Eirik Mollnes, Knut Tore Lappegård

Journal:

Journal of Clinical Apheresis

Year:

2009

Language:

english

File:

PDF, 139 KB

english, 2009

13

Bariatric surgery reduces fasting total fatty acids and increases n-3 polyunsaturated fatty acids in morbidly obese individuals

Hovland, Anders, Nestvold, Torunn, Bohov, Pavol, Trøseid, Marius, Aukrust, Pål, Berge, Rolf K., Waage-Nielsen, Erik, Retterstøl, Kjetil, Lappegård, Knut Tore

Journal:

Scandinavian Journal of Clinical & Laboratory Investigation

Year:

2017

Language:

english

File:

PDF, 826 KB

english, 2017

14

Ivabradine and nightmares: a previously unreported adverse reaction

Knut Tore Lappegård, Elisabet Nordmo

Journal:

European Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 60 KB

english, 2011

15

Bariatric surgery improves lipoprotein profile in morbidly obese patients by reducing LDL cholesterol, apoB, and SAA/PON1 ratio, increasing HDL cholesterol, but has no effect on cholesterol efflux capacity

Kjellmo, Christian Abendstein, Karlsson, Helen, Nestvold, Torunn K., Ljunggren, Stefan, Cederbrant, Karin, Marcusson-Ståhl, Maritha, Mathisen, Monica, Lappegård, Knut Tore, Hovland, Anders

Journal:

Journal of Clinical Lipidology

Year:

2017

Language:

english

File:

PDF, 568 KB

english, 2017

16

Health-related quality of life on tele-monitoring for users with pacemakers 6 months after implant: the NORDLAND study, a randomized trial

Lopez-Villegas, Antonio, Catalan-Matamoros, Daniel, Lopez-Liria, Remedios, Enebakk, Terje, Thunhaug, Hilde, Lappegård, Knut Tore

Journal:

Year:

2018

Language:

english

File:

PDF, 711 KB

english, 2018

17

Correction: Patients' experiences of remote communication after pacemaker implant: The NORDLAND study

Catalan-Matamoros, Daniel, Lopez-Villegas, Antonio, Tore-Lappegard, Knut, Lopez-Liria, Remedios

Journal:

Year:

2019

Language:

english

File:

PDF, 254 KB

english, 2019

18

Effect of complement inhibition and heparin coating on artificial surface–induced leukocyte and platelet activation

Knut Tore Lappegård, Michael Fung, Grethe Bergseth, Johan Riesenfeld, John D Lambris, Vibeke Videm, Tom Eirik Mollnes

Journal:

The Annals of Thoracic Surgery

Year:

2004

Language:

english

File:

PDF, 233 KB

english, 2004

19

No evidence of impaired endothelial function or altered inflammatory state in patients with familial hypercholesterolemia treated with statins

Anders Hovland, Inger Aagnes, Ole-Lars Brekke, John Helge Flage, Knut Tore Lappegård

Journal:

Journal of Clinical Lipidology

Year:

2010

Language:

english

File:

PDF, 155 KB

english, 2010

20

Costâutility analysis of telemonitoring versus conventional hospital-based follow-up of patients with pacemakers. The NORDLAND randomized clinical trial

Lopez-Villegas, Antonio, Catalan-Matamoros, Daniel, Peiro, Salvador, Lappegard, Knut Tore, Lopez-Liria, Remedios, AndÃ², Giuseppe

Journal:

Year:

2020

Language:

english

File:

PDF, 1.13 MB

english, 2020

21

Invited commentary

Knut Tore Lappegard

Journal:

The Annals of Thoracic Surgery

Year:

2007

Language:

english

File:

PDF, 38 KB

english, 2007

22

Complement profile and activation mechanisms by different LDL apheresis systems

Anders Hovland, Randolf Hardersen, Erik Waage Nielsen, Terje Enebakk, Dorte Christiansen, Judith Krey Ludviksen, Tom Eirik Mollnes, Knut Tore Lappegård

Journal:

Acta Biomaterialia

Year:

2012

Language:

english

File:

PDF, 1.37 MB

english, 2012

23

Addition of polyunsaturated fatty acids to statins in familial hypercholesterolemia does not affect in vitro or in vivo endothelial function

Hande, Liv, Thunhaug, Hilde, Enebakk, Terje, Ludviksen, Judith Anita, Hovland, Anders Wilhelm, Lappegård, Knut Tore

Journal:

Atherosclerosis

Year:

2017

Language:

english

File:

PDF, 283 KB

english, 2017

24

Patient tolerance regarding different low-density lipoprotein apheresis columns: Frequent minor side effects and high patient satisfaction

Anders Hovland, Randolf Hardersen, Terje Enebakk, Tom Eirik Mollnes, Knut Tore Lappegård

Journal:

Journal of Clinical Lipidology

Year:

2011

Language:

english

File:

PDF, 198 KB

english, 2011

25

Role of granulocytes and monocytes in the polyvinyl chloride-induced synthesis of interleukin 8, monocyte chemoattractant protein 1, and leukotriene B4

Knut Tore Lappegård, Grethe Bergseth, Johan Riesenfeld, Joe Sexton, Tom Eirik Mollnes

Journal:

Journal of Biomedical Materials Research Part A

Year:

2005

Language:

english

File:

PDF, 83 KB

english, 2005

26

Complement component 5 does not interfere with physiologic hemostasis but is essential for Escherichia coli- induced coagulation accompanied by Toll-like receptor 4

Landsem, Anne, Fure, Hilde, Ludviksen, Judith Krey, Christiansen, Dorte, Lau, Corinna, Mathisen, Monica, Bergseth, Grethe, Nymo, Stig, Lappegård, Knut Tore, Woodruff, Trent Martin, Espevik, Terje, Mol

Journal:

Clinical & Experimental Immunology

Year:

2018

Language:

english

File:

PDF, 815 KB

english, 2018

27

Pacemaker implantation in patients with persistent left superior vena cava

Knut Tore LappegÅrd, Jan F. Prytz, BjØrn Haug

Journal:

Heart and Vessels

Year:

2004

Language:

english

File:

PDF, 139 KB

english, 2004

28

Improved neurocognitive functions correlate with reduced inflammatory burden in atrial fibrillation patients treated with intensive cholesterol lowering therapy

Knut Tore Lappegård, Monica Pop-Purceleanu…

Journal:

Journal of Neuroinflammation

Year:

2013

Language:

english

File:

PDF, 177 KB

english, 2013

29

Hematologic and hemostatic changes induced by different columns during LDL apheresis

Anders Hovland, Randolf Hardersen, Erik Waage Nielsen, Tom Eirik Mollnes, Knut Tore Lappegård

Journal:

Journal of Clinical Apheresis

Year:

2010

Language:

english

File:

PDF, 113 KB

english, 2010

30

Recurrence and Severe Worsening of Hepatotoxicity After Reintroduction of Atorvastatin in Combination With Ezetimibe

Bergland Ellingsen, Silje, Nordmo, Elisabet, Tore Lappegård, Knut

Journal:

Clinical Medicine Insights Case Reports

Year:

2017

Language:

english

File:

PDF, 446 KB

english, 2017

31

LDL apheresis activates the complement system and the cytokine network, whereas PCSK9 inhibition with evolocumab induces no inflammatory response

Lappegård, Knut Tore, Enebakk, Terje, Thunhaug, Hilde, Ludviksen, Judith Krey, Mollnes, Tom Eirik, Hovland, Anders

Journal:

Journal of Clinical Lipidology

Year:

2016

Language:

english

File:

PDF, 925 KB

english, 2016

32

Human genetic complement deficiencies reveal a critical role for C5/C5a in the phagocytosis and killing of Neisseria meningitidis and Escherichia coli in whole blood

Bernt Christian Hellerud, Ernst Arne Høiby, Knut Tore Lappegård, Hilde Fure, Petter Brandtzæg, Morten Harboe, Tom Eirik Mollnes

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 62 KB

english, 2007

33

LDL apheresis activates the complement system and the cytokine network, whereas PCSK9 inhibition induces no inflammatory response

Hovland, Anders, Ludviksen, Judith Krey, Mollnes, Tom Eirik, Lappegård, Knut Tore

Journal:

Year:

2016

Language:

english

File:

PDF, 58 KB

english, 2016

34

Artificial surface-induced cytokine synthesis: effect of heparin coating and complement inhibition

Knut Tore Lappegård, Michael Fung, Grethe Bergseth, Johan Riesenfeld, Tom Eirik Mollnes

Journal:

The Annals of Thoracic Surgery

Year:

2004

Language:

english

File:

PDF, 243 KB

english, 2004

35

Genetic complement deficiencies dissociate the roles of human complement in the inflammatory responses: Lessons from nature

Knut Tore Lappegård, Dorte Christiansen, Anne Pharo, Ebbe Thorgersen, Bernt Christian Hellerud, Julie Lindstad, Erik Nielsen, Grethe Bergseth, Dag Fadnes, Tore Abrahamsen, Arne Høiby, Lone Schejbel, P

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 83 KB

english, 2008

36

Complement dependency of cholesterol crystal-induced inflammation – I. Pathway activation mechanisms, cytokine responses and endothelial cell activation

Stig Nymo, Eivind O. Samstad, Nathalie Niyonzima, Grethe Bergseth, Dorte Christiansen, Liv Ryan, Ole-Lars Brekke, Knut Tore Lappegård, Jan Kristian Damås, Eicke Latz, John D. Lambris, Terje Espevik, T

Journal:

Year:

2012

Language:

english

File:

PDF, 68 KB

english, 2012

37

Development of post-pericardiotomy syndrome is preceded by an increase in pro-inflammatory and a decrease in anti-inflammatory serological markers

Nora Snefjellå, Knut Tore Lappegård

Journal:

Journal of Cardiothoracic Surgery

Year:

2012

Language:

english

File:

PDF, 298 KB

english, 2012

38

Transition from LDL apheresis to evolocumab in heterozygous FH is equally effective in lowering LDL, without lowering HDL cholesterol

Lappegård, Knut Tore, Enebakk, Terje, Thunhaug, Hilde, Hovland, Anders

Journal:

Atherosclerosis

Year:

2016

Language:

english

File:

PDF, 642 KB

english, 2016

39

Three different LDL apheresis columns efficiently and equally reduce lipoprotein(a) concentrations in patients with familial hypercholesterolemia and small apolipoprotein(a) particles

Anders Hovland, Santica Marcovina, Randolf Hardersen, Terje Enebakk, Tom Eirik Mollnes, Knut Tore Lappegård

Journal:

Transfusion and Apheresis Science

Year:

2012

Language:

english

File:

PDF, 227 KB

english, 2012

40

Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric Surgery

Trøseid, Marius, Hov, Johannes R., Nestvold, Torunn Kristin, Thoresen, Hanne, Berge, Rolf K., Svardal, Asbjørn, Lappegård, Knut Tore

Journal:

Metabolic Syndrome and Related Disorders

Year:

2016

Language:

english

File:

PDF, 175 KB

english, 2016

41

The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes

Niyonzima, Nathalie, Freeley, Simon, Arbore, Giuseppina, Le Friec, Gaelle, Lappegård, Knut Tore, Mollnes, Tom Eirik, Kemper, Claudia, Espevik, Terje

Journal:

Molecular Immunology

Year:

2017

Language:

english

File:

PDF, 48 KB

english, 2017

42

Modulation by Interferons of Human Neutrophilic Granulocyte Migration

AAS, VIGDIS, LAPPEGÅRD, KNUT TORE, SIEBKE, ELSE MARIE, BENESTAD, HAAKON B.

Journal:

Journal of Interferon & Cytokine Research

Year:

1996

Language:

english

File:

PDF, 2.74 MB

english, 1996

43

Artificial Surface-Induced Inflammation Relies on Complement Factor 5: Proof From a Deficient Person

Grethe Bergseth, John D. Lambris, Tom Eirik Mollnes, Knut Tore Lappegård

Journal:

The Annals of Thoracic Surgery

Year:

2011

Language:

english

File:

PDF, 763 KB

english, 2011

44

Differential Effect of Heparin Coating and Complement Inhibition on Artificial Surface-Induced Eicosanoid Production

Knut Tore Lappegård, Johan Riesenfeld, Ole-Lars Brekke, Grethe Bergseth, John D. Lambris, Tom Eirik Mollnes

Journal:

The Annals of Thoracic Surgery

Year:

2005

Language:

english

File:

PDF, 141 KB

english, 2005

45

Lipoprotein apheresis affects lipoprotein particle subclasses more efficiently compared to the PCSK9 inhibitor evolocumab, a pilot study

Lappegård, Knut Tore, Kjellmo, Christian Abendstein, Ljunggren, Stefan, Cederbrant, Karin, Marcusson-Ståhl, Maritha, Mathisen, Monica, Karlsson, Helen, Hovland, Anders

Journal:

Transfusion and Apheresis Science

Year:

2018

Language:

english

File:

PDF, 1.09 MB

english, 2018

46

Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response

Lau, Corinna, Olstad, Ole Kristoffer, Holden, Marit, Nygård, Ståle, Fure, Hilde, Lappegård, Knut Tore, Brekke, Ole-Lars, Espevik, Terje, Hovig, Eivind, Mollnes, Tom Eirik

Journal:

Year:

2015

Language:

english

File:

PDF, 1.78 MB

english, 2015

47

The intracellular C5 system is critical to DAMP sensing and cellular responses in human monocytes

Niyonzima, Nathalie, Freeley, Simon, Arbore, Giuseppina, Le Friec, Gaelle, Lappegård, Knut Tore, Mollnes, Tom Eirik, Kemper, Claudia, Espevik, Terje

Journal:

Year:

2016

Language:

english

File:

PDF, 52 KB

english, 2016

48

Design of the GutHeart-targeting gut microbiota to treat heart failure-trial: a Phase II, randomized clinical trial

Mayerhofer, Cristiane C.K., Awoyemi, Ayodeji O., Moscavitch, Samuel D., Lappegård, Knut Tore, Hov, Johannes R., Aukrust, Pål, Hovland, Anders, Lorenzo, Andrea, Halvorsen, Sigrun, Seljeflot, Ingebjørg,

Journal:

ESC Heart Failure

Year:

2018

Language:

english

File:

PDF, 355 KB

english, 2018

49

Bariatric Surgery Reduces Risk Factors for Development of Type 2 Diabetes Mellitus in Morbidly Obese, Nondiabetic Patients

Nestvold, Torunn Kristin, Nielsen, Erik Waage, Lappegård, Knut Tore

Journal:

Metabolic Syndrome and Related Disorders

Year:

2013

Language:

english

File:

PDF, 327 KB

english, 2013

50

Oxidative burst in complement deficient patients: Lessons from nature

Ebbe B. Thorgersen, Anne Pharo, Julie K. Lindstad, Grethe Bergseth, Erik W. Nielsen, Knut Tore Lappegård, Tom Eirik Mollnes

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 55 KB

english, 2007

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